pea1 ecacc (CancerTools Org)
Structured Review

Pea1 Ecacc, supplied by CancerTools Org, used in various techniques. Bioz Stars score: 93/100, based on 102 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/pea1+ecacc/PEA1/pmc12396967-54-0-5
Average 93 stars, based on 102 article reviews
Images
1) Product Images from "Cell-intrinsic platinum response and associated genetic and gene expression signatures in ovarian cancer"
Article Title: Cell-intrinsic platinum response and associated genetic and gene expression signatures in ovarian cancer
Journal: Cancer Gene Therapy
doi: 10.1038/s41417-025-00941-5
Figure Legend Snippet: A Wound healing assay for the PEA1/PEA2 ( N = 3 independent replicates), OVCAR3 ( N = 4), OVCAR4 ( N = 4), and PEO1/4 ( N = 3) isogenic cell line pairs. Error bars represent standard deviation. * indicates p -value < 0.05 in paired t-tests and ns indicates non-significant p -value > 0.05. B Representative ALDH1A1 western blot images of all isogenic cell line pairs along with platinum resistant cell lines JHOS2 and COV362. GAPDH serves as a loading control. C CD133 and ALDH1A1 western blot images of all isogenic cell line pairs with or without cisplatin treatment at each respective cell line’s IC 50 for 72 hours. GAPDH serves as a loading control. D Volcano plot showing differential expression between isogenic platinum-resistant cell lines, comparing resistant to their sensitive counterpart. Points are color-coded based on the specific pair, and statistically significant ( | log2 fold change |>1.5, adjusted p -value < 0.05) genes are labeled by gene name.
Techniques Used: Wound Healing Assay, Standard Deviation, Western Blot, Control, Quantitative Proteomics, Labeling